"Experience has shown that it is not possible to achieve effective fluoride-based caries prevention without the development of some degree of dental fluorosis, a defect of enamel caused by excess fluoride disrupting the developing enamel prior to tooth eruption. This means that whatever methods are chosen to maintain the low level of fluoride in the mouth, the results will be accompanied by some degree of dental fluorosis. The public health administrator seeks to maximise caries reduction while minimizing fluorosis, though in many communities the relative priority accorded to these outcomes will vary."

- World Health Organisation Expert Committee on
Oral Health Status and Fluoride Use 1994